Rokuro Enmado has great talent as an exorcist, but because of trauma in his past he has given that pursuit up. That's when he meets Benio Adashino, head of the famous Adashino exorcist clan, who has moved to Tokyo from Kyoto. What will become of these two after their fateful meeting?
Benio has moved into the Seika dormitory, which puts her into conflict with Rokuro after their unpleasant first encounter. Soon a strange individual arrives at the dorm clad only in a pair of underpants. This turns out to be the leader of all exorcists, the Chief Exorcist Tsuchimikado Arima. After inviting the members of the dorm to the Five Mirror Chamber, he asks Rokuro and Benio to battle in front of exorcist authorities from around Japan. Benio wants to test Rokuro's strength, but he still wants nothing to do with being an exorcist.
Benio quickly becomes the center of attention after transferring to Rokuro and Mayura's middle school. When a Kegare attacks between classes, Benio decides to leave while Rokuro claims that their studies should take precedence over exorcist duties. But is that how he really feels?
When the kids from an elementary school soccer team are suddenly transported to Magano by Kegare, Rokuro joins Benio, Atsushi, and Shinnosuke to go to Magano and save them. But in the middle of the battle, painful memories overwhelm Rokuro, and he's unable to fight. Just then, one of the highest ranking Exorcists, the "Vermilion Bird" of the Twelve Guardians, Ikaruga Shimon, appears.
With Benio constantly leaving school for no given reason, Mayura starts to worry about her new classmate. And Rokuro starts getting back into the swing of things by joining the others on a regular Kegare exorcism.
Arima returns to Tokyo to give the Twin Star Exorcists a trial to test their skills. But it's not the kind of test they were anticipating, with an unexpected reward.
Mayura and Benio debate whether or not Rokuro should continue fighting, and an unpleasant figure from Rokuro's past arrives to test his renewed dedication to being an exorcist.
After being confronted by Yuuto, the Twin Star Exorcists are desperate to get stronger in preparation for future battles, but Benio's old master Subaru has a different kind of training in mind.
Subaru of the Twelve Guardians thinks that Benio and Rokuro need to understand each other better, but the Twin Star Exorcists aren't convinced and insist on conventional combat training. The debate comes to head in the form of a game of hide and seek: if Benio and Rokuro can track Subaru down before sunset, she'll provide the training they're asking for.
Benio and Rokuro square off against the massively powerful Kamui, but are hopelessly outmatched. What makes this Kegare so uniquely dangerous? And can the Twin Star Exorcists survive?
Benio has a vendetta against the incredibly powerful Basara, Kamui. Rokuro tries to reason with her as she insists on fighting him no matter what the cost. Can the Twin Star Exorcists overcome their most deadly enemy yet by working together?
Ryogo gets introduced to an attractive young exorcist by Fushihara, an exorcist from the neighboring area, causing him to question whether or not exorcists should pursue romantic relationships in face of the otherworldly threats that menace their lives.
After harsh words from Seigen, the Twin Stars are frustrated with how powerless they feel. Mayura decides to help cheer her exorcist friends up, in spite of a warning from her father...
Seigen attacks Yuuto, which proves useless. Yuuto fatally wounds Seigen who casts a barrier around the Twin Star Exorcists and the fainted Mayura. Seigen resolves to blow himself up; however, Rokuro and Benio escape from inside the barrier, which again Yuuto congratulates. Seigen is saved minus one arm and Rokuro manages to land a punch on Yuuto who is shocked. He then announces that he will wait for Rokuro's answer (whether he will join Yuuto on the dark side) at a place where there are precious memories for the both of them: Hiinatsuki Dormitory. Seigen and Mayura were hospitalized: Seigen undergoing surgery and Mayura still unconscious. Jissama has received information that the Twelve Guardians has been mobilized to destroy Yuuto and he gives Rokuro a package that Seigen had been wanting to give him. Inside, there is the black exorcist uniform that Seigen wore. Rokuro wears the uniform and announces to Benio that he will defeat Yuuto even with the Twelve Guardians mobilized.
Rokuro has sworn to defeat Yuto. But... how? The Twin Star Exorcists look at the facts and try to find a way to strengthen their odds against an opponent that outclasses them in nearly every way.
It's all been leading up to this. With their new Resonance abilities, the Twin Star Exorcists take the fight directly to Ijika Yuto. Will it be enough to defeat the twisted, evil exorcist?
Yuto has been dominating the Twin Star Exorcists so far, but can help from an unexpected source change the course of their battle? (Note: This episode is the point where the anime fully diverges from the manga)
Two years have passed since their battle with Yuto, and the Twin Star Exorcists have gotten better with age. But when they find something unexpected in Magano, there's no telling what it could mean for their future.
The hellish world of Magano, home of the Kegare, has begun to leak into our reality. Can the Twin Star Exorcists stop the growing influence before it spells doom for the town of Narukami?
The Twin Stars' tour across Japan to seal the Kegare-spawning Dragon Spots makes a detour to an amusement park, and Sae makes a new friend that Benio and Rokuro aren't happy about.
The Twin Star Exorcists meet a pair of twin Basara brothers, whose teamwork might be a match for our heroes' powers... And the mastermind behind the Dragon Spots finally reveals himself.
A Dragon Spot in Kumano results in a brief detour before the Twin Stars and Sae arrive in Kyoto, and they meet the strongest member of the Twelve Guardians.
The head of the Exorcist Union is attacked by the Basara responsible for the the Dragon Spots. And the Twin Star Exorcists finally learn just where Sae came from.
With the secret behind the Dragon Spots and Sae's origin revealed, the path to salvation is clear. But are the Twin Stars willing to part ways with the girl who's become like a daughter to them? And if they're not, can they help the Twelve Guardians resist the flood of Kegare coming through the Dragon Spot?
A Basara is targetting the Twin Star Exorcists, and the only one standing in his way is Shimon. But will the winged guardian save Rokuro and Benio, or be their ultimate downfall?
Chijiwa has wrapped Shimon, along with the rest of the school, in his marionette strings to force them to attack the Twin Stars. Can Rokuro, Benio, and Mayura find a way to free their friends, or will they be forced to fight?
Mayura and Seigen face off against Kuranashi, but the Basara has a wicked trick up his sleeve. Does the daughter-father team stand a chance against the mastermind of the attack on Narukami?
The Twin Star Exorcists fight the giant Kegare ravaging Narukami while it floats in the sky, as the Twelve Guardians try to make sure the floating city can return to the ground safely.
With the Twelve Guardians caught in Kuranashi's trap, it's now up to the Twin Star Exorcists to free them. But what chance do they stand against the newly powerful Basara?
Rokuro is reeling from what he has learned about his past, and Head Exorcist Arima explains the full scope of what Abe no Seimei set in motion, over a thousand years ago.
Rokuro has become the Cataclysm King, and will soon be responsible for cleansing nearly all of humanity from the Earth. Abe no Seimei offers Benio a way to turn him back to normal, but at what cost?
The greatest Exorcist of all time intends to wipe humanity's yin away in order to create a world where there will be no more free will, or individuality. Can the Twin Star Exorcists stop him?
