When the young Italian Figurelli boy, Billy, gets hurt, Orel tries to put a band-aid on him with the same color as God's skin but the band-aid doesn't blend in with Billy's skin color. However, the band-aid's blend in with other kid's skins just fine. This leads Orel to prompt the city of Moralton to segregate God's people from the Figurelli's, the only Italian-American family in the town. But this, however leads to a form of reverse racism. Soon the Figurelli's special treatment gets too out of hand for the other citizens of Moralton & they begin to go on a rampage! Now it's up to Orel's Father to set things right.
Orel befriends a stray dog and Bloberta allows Orel to keep it. After a while, the two grow very attached and Orel becomes worried that he's loving his dog Bartholomew more than Jesus. Bartholomew quickly spreads enough love around Moralton that convinces the adults that he is a danger.
Coach Stopframe goes to a meeting of a Satanic cult, taking Orel with him. However, Coach Stopframe is turned off from the cult when he sees that everyone in the meeting is overweight, wandering around in the nude, and devouring junk food refreshments.
Orel solves problems using logic. After the money from collection at church is stolen, he sets out to find out who took the money, only to discover a bigger mystery involving his mother.
After listening to Reverand Putty's sermon, Orel realises that pleasure is not righteous and starts to avoid it. Soon after, he then finds pain to be an alternative.
A new family, the Posabule's, move in next door to the Puppingtons, and Orel becomes infactuated with their daughter, Christina. However, after a little altercation between the families, he is banned from seeing her.
Orel learns about the significance of religious symbolism. In an accident, Dr. Chosenberg gets an image of Jesus in a wound. Nobody from the town wants to treat it because they see it as a sign from Heaven.
Orel is chosen by Principal Fakey to represent Diorama Elementary in the Praying Bee competition. Stressing out and unable to pray, Orel finds himself turning to the Buddhist method of meditation.
After learning that Principal Fakey is doing something wrong, Orel goes to his father to find out about wrong-doing authority figures. There, he learns that repression is the antidote to everything.
After listening to a record by Presbo the Clown about turning the other cheek, Orel continually allows himself to be beaten up by Walt, the school bully.
During a Pious Scouts camping trip, Orel discovers man's missing link and then learns the meaning of Geniusis; the worded combination about the genius of the Bible's Genesis story.
Doughy becomes infatuated with Miss Sculptham when she is only using him to gain gifts. Meanwhile, Orel learns a valuable lesson about man and woman relationships.
Reverend Putty realises that there are no sinners left in Moralton, and begins to feel lost. Orel, wanting to help, imports a number of new lost souls from the neighbouring town for Reverend Putty to save.
