Longtime ER nurse Jackie Peyton bends the rules to bring some good from a patient's senseless death, while concealing her addiction to a pain killer she gets from her boyfriend, the hospital pharmacis…

Jackie and her husband, Kevin, become concerned that their older daughter Grace is suffering from anxiety disorder; hospital administrator Mrs. Akalitus drinks Jackie's Percoset-laced coffee.

An elderly patient checks in who has been treating his heart disease with chicken soup; Jackie discusses her daughter's anxiety with Dr. O'Hara; Eddie learns that he is to be replaced by a pill-dispen…

Jackie and Kevin consider enrolling Grace in private school; the stoic Dr. O'Hara must endure the emotional thanks of a boy whose twin brother she saved; Zoey loses a patient for the first time.

Jackie breaks several rules and regulations to help a 10-year-old girl caring for her lupus-stricken mother; Mrs. Akalitus accidentally tasers herself; O'Hara treats Zoey to a meal at a four-star rest…

Jackie is caught off-guard when a nurse (Judith Ivey) she used to work with, who is dying of lung cancer, asks Jackie to help end her life. Meanwhile, Coop’s mother (Blythe Danner) is admitted with a …

A man is admitted with a steak knife sticking out of his chest. Eddie gives Jackie a Cartier bracelet for their one-year anniversary, but she rejects the gift. A baby is left in the nurses’ station an…

Jackie discovers that a new temp nurse is abusing drugs, but when she confronts him, he calls her on hypocrisy; Mrs. Akalitus still has the foundling infant left at the hospital; Coop reveals to Eddie…

Jackie admits a patient she has treated before. As his condition worsens, Zoey questions whether Jackie did enough to help him on his previous visit. Jackie’s drug use starts to cause spontaneous nose…

Jackie and Grace begin mother-daughter tap class. Coop threatens to expose Jackie for falsifying a donor’s record. Jackie has forgotten to remove her wedding ring, and needs to get it off before meeti…

Kevin decides to buy Jackie a new wedding ring. At work, the automated pill machine replaces Eddie. A movie critic is admitted with a broken elbow.

Kevin invites Jackie to a midnight rendezvous in order to give her a new wedding ring; the comatose movie critic wakes up but his tastes have radically changed.

After the confrontation with Eddie at the end of season one, it’s now a few months later. Jackie has cut ties with Eddie and is determined to dive back in and spend more time with her family. Back at …

Jackie covers for a hung-over O'Hara, while Eddie befriends Kevin and Dr. Coop gets hooked on microblogging.

O'Hara offers financial help, but Jackie and Kevin refuse to take it. Eddie and Kevin's secret friendship is revealed.

When a patient is suffering, Jackie supplies the patient with illegal marijuana to ease the pain. Meanwhile, Kevin prefers going out with Eddie rather than spend the night with Jackie and Zoey believe…

Jackie's life gets a little more complicated because of a security guard and O'Hara's longtime affair comes to light.

Unhappy about Eddie and Kevin's friendship, Jackie asks Eddie to stop spending time with Kevin. A pharmaceutical company rep provides Jackie with drugs.

Coop insults the biggest donor of the hospital while Jackie revisits her affair with Eddie.

Coop arranges a date for Georgia and Eddie while Jackie's daughter Grace starts therapy.

In order to keep her secret credit card a secret, Jackie sets up a P.O. box for the credit card bills. In the meantime, Mrs. Akalitus offers Eddie to come back as the hospital's pharmacist.

In order to get a phony prescription, Jackie falsifies an MRI. In the meantime the campaign's end has its effects on Coop and Eddie is back as the hospital's pharmacist.

Jackie has to confess that she used O'Hara's loan when her stash gets lost.

In the season finale, Jackie returns to All Saints where she must confront everyone.

In the Season 3 premiere, Jackie's marriage is strained, as is her relationship with O'Hara after the intervention; Akalitus warns the staff that nearby hospitals have closed down, straining the staff…

Eddie tells Jackie that he now considers Kevin a real friend and can no longer lie to him; Jackie is remorseful when she learns that O'Hara is looking for a new employer; Akalitus announces that All S…

Kevin's younger sister Tunie visits after a breakup with her boyfriend; Lenny prepares a surprise romantic picnic for Zoey; two street vendors are brought in after a turf war turns violent; Akalitus f…

Jackie finds a new hiding place for her pills and buries the hatchet with O'Hara, who becomes ER chief; Zoey works her first double shift; Kevin invites Eddie to a backyard barbecue; Jackie must tell …

Jackie runs out of drugs and Dr. Cooper decides to compete with Dr. O'Hara for the E.R. chief position.

Mrs. Akalitus is in a holy uproar as workers from the archdiocese remove her religious statues. Meanwhile, a new temp nurse makes his presence known in the ER, and some people don't appreciate it; Coo…

Kelly wins over the All Saints staff; Kevin finds pills in a dental floss dispenser; a patient soothes Coop's depression; Jackie pockets drugs.

Jackie accuses Kelly of being inappropriate with two flirty high school girls; Coop begins to let go of childish things; Thor counsels Akalitus on her new phone system and some deeper matters; Jackie …

Just when Jackie has run out of pills, she runs into a confrontation about the drugs from Oncology that disappeared. Coop tracks down an old girlfriend on Facebook when he decides to start his own fam…

Following HR's inquiry of the missing drugs, Mrs. Akalitus puts Jackie on probation. Meanwhile, Coop plans his wedding and Jackie's daughter Grace wants to be put on medication for her anxiety disorde…

Jackie tries to stay sober and get through probation until Dr. O'Hara has a tempting offer for her. Meanwhile Eddie believes Kevin found out about the affair and Zoey throws a party for her colleagues…

When HR demands urine samples from all the nurses, Jackie tries to avoid it as long as possible as well as her husband, who seems to have found out about her affair with Eddie.

After breaking up with Kevin, Jackie has to realize she needs professional help. Meanwhile, a new director at the hospital makes some personnel changes and Kevin finds out about Jackie and Eddie's aff…

Going through rehab, Jackie opens up about the beginning of her addiction. Meanwhile, Coop is the only one being excited about Cruz's ideas.

Worried about her daughter, Jackie leaves rehab early against her therapist's advice and finds that returning to work greatly rattles her nerves, forcing her to struggle to maintain her sobriety; Zoey…

Jackie catches Grace with a boy at a carnival and takes her, not before deleting the number from the boys phone. While at the carnival, Grace announces to Fiona and Zoey that Jackie went to rehab. Jac…

Missing her family and adjusting poorly to single life, Jackie invites Kevin to meet her at a cafe but finds herself served with divorce papers instead of lunch; an attempted double suicide trauma cas…

Jackie has a disturbing dream about using; Zoey loses her ring.

Jackie covers for Cruz when he has a panic attack; Zoey surveys her coworkers for the best ways to conduct a breakup; Akalitus enlists the staff in an elaborate charade when her mentor is admitted wit…

When Cruz learns about Jackie's rehab, he takes revenge on coworkers who have been covering up her drug problems. Meanwhile, Eddie is deposed by Kevin's lawyer; a dumped Lenny decides to take off for …

Things get out of control in the emergency room due to the recent firings and an overflow of patients who have been diverted from another hospital, causing Cruz to suffer a pulmonary episode and Jacki…

While Cruz is in care, Jackie goes over his head to get the ER under control, resulting in her dismissal from All Saints for insubordination. Jackie pulls Grace out of Catholic school. O'Hara goes int…

Victims of a bus accident are treated; two doctors join the rotation; O'Hara is happy spending time with her son; Akalitus gives Eddie his job back.

Kevin demands full custody. A bus crash patient returns after contracting sepsis. Coop threatens to quit.

After their custody meeting, Jackie rear-ends Kevin and wakes up as a patient in her own ER. Kevin accuses her of using. Coop begins covering for Carrie and taking on a lot more work. When Carrie chec…

A heavily medicated Jane Doe is brought into the ER and Jackie tasks Zoey with finding out who she is. Coop invites Carrie to dinner. Jackie faces conflict with both her daughters - Fiona has been act…

Jackie is nervous about her date with Frank, so Zoey and Thor help her get ready and Eddie offers some friendly pointers. Prentiss misdiagnoses an injured dancer, but Akalitus and Coop catch his mista…

Jackie and Grace recover from their nights of indiscretion; Carrie uses flashcards to strengthen her skills.

Akalitus forgets to hire an escort for a psych patient who then lays waste to the pharmacy; Frank cancels a lunch date with Jackie; Zoey hears Coop and Carrie having sex; Jackie worries about Frank wh…

Kevin interrupts Jackie and Frank's night. Akalitus' blood results are in and her memory loss is a result of a medication she's been taking. Zoey helps Prentiss organize his disaster of an office. Mea…

Jackie and Frank have sex for the first time and he tells her he loves her. Akalitus has an extra spring in her step. Coop wants to take his mentoring of Carrie to the next level. Kevin and Grace show…

It's Jackie's one year anniversary of sobriety and she and Frank fight about their relationship. Zoey acts very professional and rigid around Prentiss after their intimate evening. Carrie's peer revie…

Jackie's back to using again, but she's doing it differently this time: maintaining a clean and sober cover, going to 12-step meetings - even finding herself a sponsor - all the while getting her drug…

Jackie steals Dr. Roman's DEA number. Coop is recruited by a 'sperm scout.'

Coop learns his sperm count is too low for donation; Carrie gets a lucky break; Akalitus' poker habit pays off; Grace drops a bomb on Jackie.

Jackie goes off the deep end; Frank discloses a secret about his past.

Frank searches Jackie's house for drugs, but she removes them in time and hides her stash in a ladies room at the hospital. Later, Jackie bonds with a homeless, alcoholic nun; and finds comfort in the…

Jackie's fake identity is compromised when it's learned that Carrie's DEA number has been stolen by a woman named Nancy Wood. Meanwhile, Jackie worries about her dwindling bank account and lack of pil…

Jackie is ambushed by Antoinette. Coop's dream finally comes true.

Jackie detoxes at home - with help. Frank raises an objection about Grace.

Jackie learns about a DEA investigation at the hospital that will require her to take a urine test, so she plots to get around it. Meanwhile, Kevin and Mia plan their wedding; the homeless nun returns…

Jackie breaks up with Frank and tries to separate herself from the people closest to her so she can keep using drugs. Meanwhile, Carrie forgets Coop's 40th birthday; the DEA investigation intensifies;…

Jackie reluctantly attends Kevin's wedding. Carrie makes demands on Coop.

Coop gets a surprise. Jackie hits the road. Season finale.

Picking up with her arrest, Jackie suffers through detox.

Jackie gets inventive, setting her sights on returning to All Saints.

Jackie's back at All Saints - but back to square one in a new role.

Still strapped for cash, Jackie's dealing takes a surprising turn.

Jackie stirs up trouble for the developers. Coop preps for his last day.

Zoey leads the ER nurses on a walkout. Jackie battles her cravings.

Jackie and Eddie make a purge their stash. Dr. Prince and Akalitus bond.

Dr. Prince enlists Jackie's help with a patient. Thor reveals a secret.

Zoey finally confronts Jackie. Dr. Prince attracts a mob to All Saints.

An unexpected knock at the door puts Jackie and Eddie in jeopardy.

Jackie is forced to perform a procedure on her own. Zoey learns a secret.

Jackie gets offered a job - and wants Zoey to come with her. Series finale.