Jackie's back to using again, but she's doing it differently this time: maintaining a clean and sober cover, going to 12-step meetings - even finding herself a sponsor - all the while getting her drugs from the towel girl at the gym. Meanwhile at All Saints, Zoey finds out that everyone knows about her 'secret' relationship with Prentiss. Season premiere.
Frank searches Jackie's house for drugs, but she removes them in time and hides her stash in a ladies room at the hospital. Later, Jackie bonds with a homeless, alcoholic nun; and finds comfort in the arms of a fellow drug user. Meanwhile, Zoey confronts Prentiss about his dissatisfaction and encourages him to do what he loves.
Jackie's fake identity is compromised when it's learned that Carrie's DEA number has been stolen by a woman named Nancy Wood. Meanwhile, Jackie worries about her dwindling bank account and lack of pills; and Prentiss gives Zoey a shocking message.
Jackie learns about a DEA investigation at the hospital that will require her to take a urine test, so she plots to get around it. Meanwhile, Kevin and Mia plan their wedding; the homeless nun returns in worse shape than ever; and Coop and Carrie find a way to skirt their no sex in the hospital rule.
Jackie breaks up with Frank and tries to separate herself from the people closest to her so she can keep using drugs. Meanwhile, Carrie forgets Coop's 40th birthday; the DEA investigation intensifies; and Zoey decides to become a nurse practitioner.
