A salesman keeps bugging Stimpy to buy a new product, Salve. Ren gets very annoyed and tries to get him out of his house, but when he finally needs it, Stimpy buys all the cans of Salve.
Ren & Stimpy have been hitch hiking for three years. They finally get a ride... from crazed circus midgets who kidnap various people, because they are in desperate need of an audience.
After Stimpy gets out of the shower, he finds that there is not a pair of pants in the house. Ignoring Ren, who tells him that clothes are for humans, and that he doesn't need pants, he tries multiple times to find a pair of pants, without much luck. He is shunned by the outside world because he is nude. He eventually gets lost in the forest, cold, naked, and embarrassed.
Stimpy squeezes, and a stench is born. Ren thinks it's just a stinky fantasy, but when Stinky floats away, Stimpy abandons his friend to search through rain and snow and dark of night. It'll take a Christmas miracle for Stinky to return to his warm, snugly home!
Stimpy is making a cartoon when Ren appears and tries to persuade Stimpy that cartoons aren't good for the brain. When Stimpy discovers that Ren is bad for drawing he makes him producer of the cartoon. Ren takes over the credits of the cartoon and Stimpy works in a slavering way until the cartoon is finished and are invited to show the cartoon to Wilbur Cobb, "the godfather of animation".
Stimpy walks in on Ren while he tortures an ant. After concluding that Ren has no conscience, Stimpy lets Ren borrow his concience, played by guitar player Jiminy Lummox.
Ren & Stimpy are the hosts of a popular fishing show. They set out on a mission to catch the legendary foul mouth Bass, Albert, and Wilbur Cobb escapes from prison to come along with them.
Ren's feeling fine on his 10th birthday until Stimpy reminds him that he's 70 years old in "dog years". Ren prepares for death with a will, a fake funeral, and the search for the perfect coffin.
