Ren and Stimpy get jobs as bellhops and must make sure that no one finds out who is living in the top two floors of the hotel, but their curiosity gets the best of them.
Ren is getting ready for the annual Dog Lodge meeting and Stimpy begs to come along (due to the fact that the lodge is for dogs only since he's a cat) in which Ren agrees to bring him to the Dog Lodge.
When Ren and Stimpy find out they are about to be cancelled, Ren comments that they'll do anything to keep the show on going, so the producer makes "a twist in chemistry" by making Stimpy the skinny jerk and Ren as the fat idiot.